Sulfa - Bactrim
What Is Bactrim (Sulfamethoxazole & Trimethoprim)?
Bactrim is the brand name of the generic antibiotic sulfamethoxazole trimethoprim (sometimes called co-trimoxazole).
The drug is a combination of two antibiotics: It's one part trimethoprim (a synthetic drug), and five parts sulfamethoxazole (a sulfonamide drug).
Bactrim works against bacteria in the following types of infections:
Bactrim is also sometimes prescribed for other types of bacterial pneumonia, for acne, and for preventing urinary tract infections.
The Food and Drug Administration (FDA) first approved Bactrim in 1973. The drug is made by Mutual Pharmaceutical Co.
Bactrim shouldn't be used by people who:
- Are hypersensitive to trimethoprim or sulfonamide drugs (or have sulfa allergies)
- Have suffered from thrombocytopenia (low blood platelet count) after taking trimethoprim or sulfonamides
- Have megaloblastic anemia (low red blood cell count) caused by a folic acid deficiency
- Are less than two months old
- Have severe liver damage or poor kidney function that cannot be monitored
Though rare, the use of sulfonamides can cause severe and potentially fatal reactions, such as Stevens-Johnson syndrome.
Stop taking Bactrim and call your doctor right away if you develop a rash after taking Bactrim, and get emergency medical help if the rash starts to become severe or you feel like you are having an allergic reaction.
Other rare but serious reactions have included toxic epidermal necrolysis (a life-threatening skin condition), acute liver failure, agranulocytosis (severely low levels of white blood cells), aplastic anemia (when the body stops blood cell production), and other blood-related disorders.
As with most other antibiotics, Bactrim may cause prolonged diarrhea resulting from a difficult-to-treatClostridium difficile (C. diff)infection.
Before taking Bactrim, also tell your doctor if you have:
- Folic acid deficiency
- Kidney or liver disease
- Severe allergies
- Bronchial asthma
- An inherited blood disease called glucose-6-phosphate dehydrogenase (G-6-PD) deficiency
- A thyroid disorder
- Porphyria, an inherited enzyme disease that may cause skin and nervous system problems
- Phenylketonuria, an inherited disorder that can cause intellectual disabilities if a strict diet is not maintained
Pregnancy and Bactrim
Bactrim may harm a developing fetus.
The drug has a warning that if you take it when you're pregnant, it can cause such birth defects as urinary tract defects, cleft lip or palate, or club feet.
Before taking Bactrim, tell your doctor if you are pregnant or may become pregnant.
It should only be used during pregnancy if the benefits clearly outweigh the potential harms to the unborn child.
You should not breastfeed when taking Bactrim. The drug is excreted in breast milk and has the potential to harm breastfeeding infants, especially if they are ill, stressed, or premature.
Bactrim Coupons and Prices
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Bactrim Side Effects
The most common side effect of Bactrim is nausea. Call your doctor if it worsens or does not go away, or if you experience:
Some other common side effects might be an early sign of a more severe reaction, so if you experience the following, stop taking the drug and call your doctor right away:
Bactrim is associated with numerous rare side effects. Although they are not likely to require medical attention, you should tell your doctor if you have:
- Abdominal pain or diarrhea
- Mild tiredness
- Mild weakness
Serious Side Effects of Bactrim
Tell your doctor right away or get emergency medical help if you experience:
Be sure to tell your doctor about any medications, illegal and recreational drugs, herbal remedies, and nutritional or dietary supplements you're taking.
In particular, tell your doctor if you are taking any of the following, which can interact with Bactrim:
Bactrim and Other Interactions
Bactrim may produce incorrect test results if you are monitoring the health of your kidneys with certain tests (such as creatinine).
It may also interfere with blood tests to measure methotrexate (Trexall), a drug used to treat certain types of cancer, autoimmune diseases (such as rheumatoid arthritis), and psoriasis.
Bactrim tablets are white and round and contain 80 milligrams (mg) of trimethoprim and 400 mg of sulfamethoxazole.
Bactrim DS tablets are white and oval, containing 160 mg of trimethoprim and 800 mg of sulfamethoxazole.
Take the medication as directed by your doctor until you finish the prescription, even if you feel better.
Failure to do so may help create bacteria that are resistant to treatment.
Signs and symptoms of Bactrim overdose include:
- Fluctuating pain in the abdomen
- Nausea and vomiting
- Bloody urine
- Anemia or other blood disorders
If you suspect an overdose, you should contact a poison-control center or emergency room immediately.
You can reach a poison-control center at (800) 222-1222.
If someone else has collapsed or isn't breathing, call 9-1-1 for emergency help right away.
Video: BULA DE BACTRIM – INFECÇÕES POR BACTÉRIAS
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